Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

1.5K
Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
1.5K
Spin–Spin Coupling: One-Bond Coupling01:17

Spin–Spin Coupling: One-Bond Coupling

1.2K
Coupling interactions are strongest between NMR-active nuclei bonded to each other, where spin information can be transmitted directly through the pair of bonding electrons. While nuclei polarize their electrons to the opposite spins, the bonding electron pair has opposite spins. Configurations with antiparallel nuclear spins are expected to be lower in energy. When coupling makes antiparallel states more favorable, J is considered to have a positive value. The one-bond coupling constant, 1J,...
1.2K
Spin–Spin Coupling Constant: Overview01:08

Spin–Spin Coupling Constant: Overview

1.2K
In bromoethane, the three methyl protons are coupled to the two methylene protons that are three bonds away. In accordance with the n+1 rule, the signal from the methyl protons is split into three peaks with 1:2:1 relative intensities. The methylene protons appear as a quartet, with the relative intensities of 1:3:3:1.
Qualitatively, any spin plus-half nucleus polarizes the spins of its electrons to the minus-half state. Consequently, the paired electron in the hydrogen–carbon bond must...
1.2K
Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)01:22

Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)

1.3K
Vicinal or three-bond coupling is commonly observed between protons attached to adjacent carbons. Here, nuclear spin information is primarily transferred via electron spin interactions between adjacent C‑H bond orbitals. This generally favors the antiparallel arrangement of spins, so 3J values are usually positive.
The extent of coupling depends on the C‑C bond length, the two H‑C‑C angles, any electron-withdrawing substituents, and the dihedral angle between the...
1.3K
NMR Spectroscopy: Spin–Spin Coupling01:08

NMR Spectroscopy: Spin–Spin Coupling

3.3K
The spin state of an NMR-active nucleus can have a slight effect on its immediate electronic environment. This effect propagates through the intervening bonds and affects the electronic environments of NMR-active nuclei up to three bonds away; occasionally, even farther. This phenomenon is called spin–spin coupling or J-coupling. Coupling interactions are mutual and result in small changes in the absorption frequencies of both nuclei involved. While nuclei of the same element are involved...
3.3K
Chirality in Nature02:30

Chirality in Nature

13.3K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
13.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precise Quantum Chemistry calculations with few Slater Determinants.

Nature communications·2026
Same author

Excitation Energy Transfer in an Intermediate Regime: A Multiconfigurational Gaussian Wavepacket Study of a Light-Harvesting Supramolecular Dyad.

The journal of physical chemistry letters·2026
Same author

Spacer cation design: promoting vertical orientation in layered perovskites.

EES solar·2026
Same author

Reduced density matrices and phase-space distributions in thermofield dynamics.

The Journal of chemical physics·2026
Same author

A Haldane-Anderson Hamiltonian model for hyperthermal hydrogen scattering from a semiconductor surface.

The Journal of chemical physics·2026
Same author

Chemisorption vs. Physisorption in Perfluorinated Zn(II) Porphyrin-SnO<sub>2</sub> Hybrids for Acetone Chemoresistive Detection.

Molecules (Basel, Switzerland)·2025

Related Experiment Video

Updated: Apr 22, 2026

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser
09:00

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser

Published on: June 28, 2018

9.3K

Spin-orbit coupling and beyond in chiral-induced spin selectivity.

Ruggero Sala1,2, Sushant Kumar Behera3, Abhirup Roy Karmakar4

  • 1Department of Chemistry, Università degli Studi di Pavia and INSTM, Via Taramelli 12, 27100 Pavia, Italy.

Nanoscale
|April 21, 2026
PubMed
Summary

Chiral-Induced Spin Selectivity (CISS) enables spin-polarized electron transport in chiral materials without magnetic fields. Molecular chirality and electric fields enhance spin-orbit coupling, driving spin-selective phenomena in nanomaterials.

More Related Videos

Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope
09:06

Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope

Published on: March 24, 2019

6.6K
Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

9.9K

Related Experiment Videos

Last Updated: Apr 22, 2026

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser
09:00

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser

Published on: June 28, 2018

9.3K
Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope
09:06

Visualizing Uniaxial-strain Manipulation of Antiferromagnetic Domains in Fe1+YTe Using a Spin-polarized Scanning Tunneling Microscope

Published on: March 24, 2019

6.6K
Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

9.9K

Area of Science:

  • Condensed Matter Physics
  • Materials Science
  • Quantum Chemistry

Background:

  • Chiral-Induced Spin Selectivity (CISS) is a phenomenon where chiral molecules induce spin polarization in electron transport without external magnetic fields.
  • This effect is particularly intriguing in light-element materials with inherently weak spin-orbit coupling (SOC).

Purpose of the Study:

  • To analyze the microscopic origins of CISS in chiral systems.
  • To critically evaluate existing theoretical models for CISS, considering symmetry and reciprocity.
  • To explore recent advancements linking chirality density to spin currents.

Main Methods:

  • Review and analysis of existing theoretical models and experimental findings on CISS.
  • Application of relativistic quantum mechanics and complete multipole representations.
  • Investigation of symmetry constraints, phenomenological assumptions, and Onsager reciprocity.

Main Results:

  • Molecular chirality, local electric fields, and dynamic distortions effectively enhance SOC, leading to spin-dependent transport.
  • A direct relationship between chirality density and spin current pseudoscalars has been established through field-theoretic approaches.
  • Existing models are assessed for their validity and limitations.

Conclusions:

  • CISS arises from the interplay of molecular chirality and enhanced effective SOC, enabling spin-selective transport.
  • Field-theoretic insights provide a foundation for understanding CISS.
  • Light-element chiral nanomaterials offer tunable platforms for nanoscale spin engineering.