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Related Concept Videos

Language and Cognition01:27

Language and Cognition

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Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
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The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
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Updated: Apr 22, 2026

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Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS.

Wendy Qi1, Katharine Lee1, Kerry C Nix1

  • 1Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, California, USA.

Annals of Clinical and Translational Neurology
|April 21, 2026
PubMed
Summary
This summary is machine-generated.

Children with Self-Limited Epilepsy with Centrotemporal Spikes (SeLECTS) show increased brain connectivity between motor and language areas. This heightened connectivity is linked to poorer phonological awareness in affected children.

Keywords:
Benign Epilepsy with Centrotemporal Spikes (BECTS)Childhood Epilepsy with Centrotemporal Spikes (CECTS)Rolandic Epilepsyelectroencephalogramfunctional connectivitylanguage processingpediatric epilepsyphonological awareness

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Area of Science:

  • Neuroscience
  • Epilepsy Research
  • Cognitive Neuroscience

Background:

  • Self-Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is characterized by language impairments, despite seizures originating in the motor cortex.
  • This suggests abnormal interactions between different brain networks are involved.

Purpose of the Study:

  • To investigate if functional connectivity during language tasks in SeLECTS predicts language performance.
  • To explore the relationship between motor and language network connectivity and language abilities in children with SeLECTS.

Main Methods:

  • High-density EEG was recorded from children with SeLECTS and controls during verb generation, repetition, and resting tasks.
  • Phonological awareness was assessed using the Comprehensive Test of Phonological Processing-2.
  • Functional connectivity between motor and language regions was measured using the weighted Phase Lag Index (wPLI).

Main Results:

  • Children with SeLECTS exhibited significantly elevated connectivity between motor and language regions during language tasks.
  • Motor-to-frontal connectivity was higher in SeLECTS during verb generation and repetition.
  • Elevated interhemispheric connectivity during language tasks correlated with poorer phonological awareness in SeLECTS.

Conclusions:

  • Task-specific connectivity abnormalities are a hallmark of SeLECTS.
  • Interhemispheric connectivity patterns may be associated with language deficits in SeLECTS, suggesting potential therapeutic targets.