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Updated: Apr 23, 2026

OLIgo Mass Profiling OLIMP of Extracellular Polysaccharides
Published on: June 20, 2010
Clusteroluminescent Monosaccharide, Oligosaccharide, and Polysaccharide
Yuchen Cen1, Mingxiu Lv1, Tianxiao Yao1
1Green Polymer Graduate Course (Class of 2025), MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310058, China.
Abstract:
The development of green polymers is of critical importance for environmental sustainability and biomedical applications. Saccharides, as abundant natural polymers, have been widely used in food, agriculture, medicine, and medical devices. This review systematically summarizes the unique photophysical properties of monosaccharides, oligosaccharides, and polysaccharides that exhibit pronounced clusteroluminescence (CL). The emission mechanism based on through-space conjugation (TSC) is discussed, and negative hyperconjugation is further introduced, using polyethylene glycol as a representative structure, as an important weak interaction that modulates the electronic structures of CL materials. In addition, several unresolved issues in current CL research, extending beyond saccharide systems, are highlighted. It is anticipated that this review will stimulate further development of CL-based green polymers by advancing mechanistic understanding and enabling emerging functional applications.
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