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Updated: Apr 23, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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Social determinants of health and outcome of extremely preterm infants: A Swiss population-based study

Marion Decaillet1,2,3, Timea Hasenauer4, Juliane Schneider1,3

  • 1Clinic of Neonatology, Department of Mother-Woman-Child, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Plos One
|April 21, 2026
PubMed

Insights

Social determinants of health (SDoH) like nationality and socioeconomic status (SES) minimally impacted perinatal outcomes for extremely preterm (EPT) infants in Switzerland. However, these SDoH significantly influenced neurodevelopmental outcomes at 18 months.

Area of Science:

  • Neonatal research
  • Pediatric health outcomes
  • Social epidemiology

Background:

  • Social determinants of health (SDoH) impact preterm infant outcomes, but Swiss data are limited.
  • Investigating SDoH in Swiss extremely preterm (EPT) infants is crucial for understanding disparities.

Purpose of the Study:

  • To assess associations between maternal nationality, parental socioeconomic status (SES), and language with perinatal and 18-month outcomes in Swiss EPT infants.
  • To identify potential SDoH-related factors influencing EPT infant development in Switzerland.

Main Methods:

  • Retrospective analysis of EPT infants (born 2009-2020) evaluated at 18 corrected months.
  • Utilized Bayley Scales of Infant Development and neurological examinations.
  • Compared outcomes based on maternal nationality, parental SES, and parental language.

Main Results:

  • Nationality and SES influenced neonatal factors like multiple births and feeding practices.
  • No significant association between parental language and neonatal outcomes.
  • At 18 months, cognitive scores varied by nationality and SES; language scores differed by parental language.

Conclusions:

  • SDoH showed minimal association with perinatal outcomes in Swiss EPT infants.
  • Maternal nationality, parental SES, and language significantly impacted 18-month neurodevelopmental outcomes.
  • These findings highlight the importance of addressing SDoH in EPT infant care and follow-up.
Abstract

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