Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulse rhythm01:30

Pulse rhythm

1.6K
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
1.6K
Holter Monitor: 24-Hour Monitoring01:23

Holter Monitor: 24-Hour Monitoring

5.5K
Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
5.5K
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

2.9K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A paradoxical impact of alcohol on sleep-memory coupling.

Current biology : CB·2026
Same author

Tanycyte BMAL1 regulates high-fat diet weight gain and shapes arcuate neurogenesis in female mice.

Cell reports·2026
Same author

Clock gene signature predicts insomnia and links to sleep/circadian parameters.

Translational psychiatry·2026
Same author

Glucose is dynamically regulated by time of day in humans and Drosophila.

PLoS biology·2026
Same author

Endocytosis at the mouse blood brain barrier is elevated during sleep.

bioRxiv : the preprint server for biology·2026
Same author

TracMyAir: Smartphone-enabled spatiotemporal estimates for inhaled doses of particulate matter and ozone to personalize health outcomes.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: Apr 23, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
08:36

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

13.3K

Quantifying sleep wake rhythms in the hospital environment with digital technologies.

Carsten Skarke1,2,3, Nadim El Jamal4, Michael V Genuardi5

  • 1Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. cskarke@pennmedicine.upenn.edu.

NPJ Digital Medicine
|April 21, 2026
PubMed
Summary

Hospitalization disrupts patients' natural body rhythms, with increased nighttime awakenings and decreased cognitive function observed in cardiac surgery patients. These disruptions highlight the need for interventions to improve sleep and recovery.

More Related Videos

Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

7.3K
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

16.7K

Related Experiment Videos

Last Updated: Apr 23, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
08:36

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

13.3K
Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

7.3K
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

16.7K

Area of Science:

  • Circadian Biology
  • Sleep Medicine
  • Postoperative Care

Background:

  • Postoperative clinical care environments can disrupt circadian rhythms, potentially impacting patient health outcomes.
  • Maintaining circadian alignment is crucial for recovery and well-being after surgery.

Purpose of the Study:

  • To explore and assess circadian desynchronization in elective cardiac surgery patients during preoperative, in-hospital, and post-discharge phases.
  • To identify environmental and behavioral factors contributing to circadian disruption in a hospital setting.

Main Methods:

  • Collected over 1.8 million data points using 11 remote sensors across different care settings.
  • Monitored environmental factors (light, sound, temperature) and patient behavior (sleep, activity).
  • Assessed cognitive function and behavioral-physiological rhythms in 13 elective cardiac surgery patients.

Main Results:

  • Hospital environments exhibited frequent nighttime activity, elevated sound levels, and inadequate diurnal temperature variation.
  • Circadian rhythms were disrupted and phase-shifted in-hospital, with a significant increase in nighttime wakefulness (10.7% to 34.8%).
  • Cognitive function scores decreased, and 31% of patients experienced transient mild impairment.

Conclusions:

  • Hospitalization significantly disrupts patient circadian rhythms and sleep patterns, negatively affecting cognitive function.
  • Environmental factors within the hospital contribute to circadian desynchronization.
  • Findings will inform a controlled trial to mitigate these disruptors and improve patient outcomes.