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Anticoagulation versus Antiplatelet Therapy in COVID-19-Related Stroke: Navigating Clinical Dilemmas in a Critically

Bo-Ying Huang1, Kuan-Hung Lin2, Kuan-Hsien Lu2

  • 1Department of Neurology, Chi Mei Medical Center, Chiali, Tainan, Taiwan.

Case Reports in Neurology
|April 22, 2026
PubMed

Insights

COVID-19-related stroke in cirrhosis patients presents a treatment challenge. A mechanism-guided approach, considering thromboinflammation and bleeding risk, is crucial for therapy selection over standard antiplatelet or anticoagulant use.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Hepatology

Background:

  • Coronavirus disease 2019 (COVID-19) can trigger thromboembolic events, including stroke.
  • Cirrhosis patients have a complex bleeding and clotting risk profile, further complicated by COVID-19.
  • Standard stroke treatment guidelines may not apply to COVID-19-related thromboinflammatory strokes in cirrhosis.
Abstract

Keywords:
Antithrombotic therapyCOVID-19Ischemic stroke

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