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Lymphangioma-Induced Macroglossia in an Adolescent: A Case Report
Arezoo Heidary1, Mojtaba Mehrabanian2
1Department of Oral and Maxillofacial Diseases, Faculty of Dentistry Yazd Shahid Sadoughi University of Medical Sciences Yazd Iran.
Clinical Case Reports
|April 22, 2026
Summary
Adolescent macroglossia caused by lymphangioma is rare. Sclerotherapy effectively reduced tongue size, improving function and quality of life in a 14-year-old patient.
Area of Science:
- Medicine
- Pediatrics
- Dermatology
Background:
- Lymphangioma is a congenital lymphatic malformation, typically affecting the head and neck.
- Macroglossia from lymphangioma in adolescents is uncommon, impacting oral function and quality of life.
Purpose of the Study:
- To report a rare case of adolescent-onset lymphangioma causing macroglossia.
- To highlight the effectiveness of sclerotherapy as a treatment option.
Main Methods:
- A 14-year-old female presented with progressive tongue enlargement.
- Diagnosis was confirmed via histopathology after excluding other conditions like hemangioma.
- Treatment involved sclerotherapy.
Main Results:
- Sclerotherapy led to significant reduction in tongue size.
- Oral function and related symptoms improved post-treatment.
- No recurrence or major complications were observed during follow-up.
Conclusions:
- Early diagnosis and intervention are crucial for lymphangioma-induced macroglossia.
- Sclerotherapy presents a minimally invasive and effective alternative to surgical excision.
- This case emphasizes the importance of a multidisciplinary approach for optimal patient outcomes.
