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Updated: Apr 23, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
TAVR for Elderly Patient With Bicuspid Aortic Stenosis, Severe Horizontal Heart, and Ascending Aorta Dilation
Xinyi Tang1, Qing Lu1, Huayiyang Zou1
1Department of Cardiology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Background:
Transcatheter aortic valve replacement (TAVR) has advanced from an emerging technology to a standard therapeutic option for high-risk patients with symptomatic severe aortic stenosis. Procedural risk correlates strongly with aortic root anatomy. In elderly patients with bicuspid aortic valves, concomitant horizontal cardiac orientation and ascending aortic dilation confer markedly higher procedural risk.
Case Summary:
We report an elderly patient with a bicuspid aortic valve, severe horizontal aortic root angulation (88°), and ascending aortic dilation (approximately 60 mm). The presence of an ascending aortic aneurysm supported the indication for surgical intervention. Given the substantial technical complexity and perioperative risk of open-heart surgery, TAVR was selected as a safer alternative.
Discussion:
This case demonstrates that TAVR remains feasible in elderly patients with complex anatomy unsuitable for surgery, despite increased procedural challenges and risk.
Take-Home Message:
In elderly patients with severe aortic stenosis and anatomically complex aortic pathology, TAVR should be considered a clinically viable treatment strategy.
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