Screening for Hepatocellular Carcinoma with Ultrasound.

Area of Science:

• Radiology
• Hepatology
• Oncology

Background:

• Hepatocellular carcinoma (HCC) is a significant global health concern.
• Accurate and sensitive imaging is crucial for early detection and management of HCC.
• The Liver Imaging Reporting and Data System (LI-RADS) provides standardized criteria for liver lesion characterization.

Purpose of the Study:

• To review the technical requirements and implementation recommendations for LI-RADS v2024.
• To provide guidance on establishing and maintaining successful HCC screening programs utilizing LI-RADS v2024.
• To present the evidence supporting the adoption and use of LI-RADS v2024 for HCC surveillance.

Main Methods:

• Review of LI-RADS v2024 guidelines and technical specifications.
• Analysis of existing literature and evidence supporting LI-RADS implementation.
• Synthesis of best practices for screening program development and maintenance.

Main Results:

• LI-RADS v2024 demonstrates increased sensitivity in identifying hepatocellular carcinoma.
• The updated system offers improved accuracy in characterizing liver lesions relevant to HCC.
• Evidence supports the clinical utility of LI-RADS v2024 in HCC surveillance.

Conclusions:

• LI-RADS v2024 represents an advancement in HCC detection sensitivity.
• Adoption of LI-RADS v2024 is recommended for all practices performing HCC surveillance via ultrasound.
• Successful implementation requires attention to technical requirements and program management.