Advancements in Screening Strategies for Early-Onset Colorectal Cancer (EOCRC)

Area of Science:

• Gastroenterology
• Public Health
• Radiology

Background:

• Rising incidence of early-onset colorectal cancer (CRC) in younger populations presents a significant public health challenge.
• Current screening guidelines are under review due to shifting epidemiologic patterns.

Purpose of the Study:

• To analyze recent epidemiologic trends and causative factors in early-onset CRC.
• To evaluate current and emerging colorectal cancer screening modalities, focusing on CT colonography and AI.
• To inform clinical and policy decisions regarding colorectal cancer screening.

Main Methods:

• Review of recent epidemiologic data on colorectal cancer incidence in younger adults.
• Analysis of current structural and nonstructural screening modalities for colorectal cancer.
• Examination of the role of computed tomography (CT) colonography and artificial intelligence (AI) in CRC screening.

Main Results:

• Epidemiologic shifts indicate a growing need for updated screening strategies for colorectal cancer.
• CT colonography offers specific advantages and limitations in efficacy, cost, and patient experience.
• Artificial intelligence demonstrates potential to enhance the diagnostic accuracy of existing screening tests.

Conclusions:

• Evolving screening guidelines are necessary to address the increasing burden of early-onset colorectal cancer.
• CT colonography and AI integration represent promising advancements in colorectal cancer screening.
• Informed clinical and policy decisions are crucial for effective early detection and management of colorectal cancer.