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Pseudo-Acute Kidney Injury Caused by a Radiation-Induced Bladder Rupture.

Makoto Ando1, Akiko Kudo1, Takuya Yamamoto1

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Summary
This summary is machine-generated.

Bladder rupture after uterine cancer treatment can mimic acute kidney injury (AKI). Prompt diagnosis and catheter drainage, not dialysis, resolved renal dysfunction in this case.

Keywords:
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Area of Science:

  • Urology
  • Oncology
  • Nephrology

Background:

  • Chemoradiotherapy for uterine cancer can cause severe complications.
  • Bladder rupture is a rare but serious sequela.
  • Urinary ascites from bladder perforation can elevate creatinine and BUN, mimicking acute kidney injury (AKI).

Purpose of the Study:

  • To report a case of pseudo-AKI caused by bladder rupture post-chemoradiotherapy.
  • To highlight the diagnostic challenges in differentiating pseudo-AKI from true AKI.
  • To emphasize the importance of considering bladder rupture in patients with pelvic radiotherapy history presenting with ascites and renal dysfunction.

Main Methods:

  • Case report presentation.
  • Review of patient history, symptoms, and laboratory parameters.
  • Clinical assessment and diagnostic imaging (implied).
  • Management with urethral catheter drainage.

Main Results:

  • A patient developed urinary ascites and elevated renal parameters after chemoradiotherapy.
  • Initial treatment with hemodialysis was temporary.
  • Renal function significantly improved after urethral catheter placement and drainage of ascites.
  • The patient's condition was diagnosed as pseudo-AKI due to bladder rupture.

Conclusions:

  • Bladder rupture should be considered in the differential diagnosis of renal dysfunction in patients with a history of pelvic radiotherapy.
  • Nonspecific symptoms of bladder rupture can delay diagnosis.
  • Urethral catheterization and drainage can effectively manage pseudo-AKI secondary to bladder rupture.