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Updated: Apr 24, 2026

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
Published on: April 2, 2012
A case of adrenomyeloneuropathy with recurrent Mollaret's meningitis due to herpes simplex virus type 2
Yumiko Nakamura1, Toshiyuki Kakumoto1,2, Munehiro Yoshimoto1
1Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
Abstract:
We report a case of adrenomyeloneuropathy caused by a novel ABCD1 variant complicated by recurrent herpes simplex virus type 2 meningitis, with no evidence of either any clinical or radiological progression. Given previous reports describing temporal associations between infections and the recognition of cerebral adrenoleukodystrophy (ALD), careful continuous observation of the present case with attention to the development of cerebral ALD is required. The early recognition of cerebral ALD is mandatory to achieve better outcomes with hematopoietic stem cell transplantation.
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