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Updated: Apr 24, 2026

Studying Effects of Cigarette Smoke on Pseudomonas Infection in Lung Epithelial Cells
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Periodontal Disease in Smokers.

Shaili Pradhan1, Anugya Karanjit1, Krishna Prasad Lamichhane1

  • 1National Academy of Medical Sciences, Mahabauddha, Kathmandu, Nepal.

Journal of Nepal Health Research Council
|April 23, 2026
PubMed
Summary

Smoking significantly increases the risk of periodontal disease, with nearly all smokers experiencing gingival bleeding and over 85% showing signs of severe gum disease. Smoking cessation programs are crucial for improving periodontal health.

Keywords:
Gingival bleeding; loss of attachment; periodontal pocket; periodontitis; smoking.

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Area of Science:

  • Dental Science
  • Public Health

Background:

  • Smoking is a well-established risk factor for periodontal disease, negatively impacting oral microbiota, immune responses, and periodontal healing.
  • Previous research indicates a strong correlation between smoking habits and the prevalence and severity of periodontal conditions.

Purpose of the Study:

  • To assess the prevalence and status of periodontal disease among a smoker population.
  • To evaluate the necessity of smoking cessation and awareness initiatives for enhancing periodontal health outcomes.

Main Methods:

  • A cross-sectional observational study was conducted with 231 smokers at Bir Hospital's dental outpatient department.
  • The Community Periodontal Index (CPI) modified index was utilized to assess periodontal status.
  • Data were analyzed to compare the impact of smoking on periodontitis across different smoking statuses.

Main Results:

  • Gingival bleeding was observed in 99.13% (229/231) of smokers.
  • Periodontal pockets exceeding 3mm were present in 90.47% (209/231) of participants.
  • Loss of attachment greater than 3mm was recorded in 85.71% (198/231) of the study group.

Conclusions:

  • Smokers exhibited a significantly higher prevalence of gingival bleeding, periodontal pockets, and loss of attachment.
  • These findings underscore the critical importance of implementing smoking cessation and awareness programs to mitigate periodontal disease progression.