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Herniated Intervertebral Disc l: Introduction01:29

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Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
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Segmental Infantile Hemangiomas That Involve the Midline Define Risk for LUMBAR Syndrome.

D Metry1, E Fernandez-Faith2, A Haggstrom3

  • 1Department of Dermatology, Driscoll Children's Hospital, Texas A&M University, Corpus Christi, Texas, USA.

Pediatric Dermatology
|April 23, 2026
PubMed
Summary
This summary is machine-generated.

Segmental infantile hemangiomas on the midline indicate risk for LUMBAR syndrome, warranting evaluation. Strictly lateral lesions without midline involvement do not pose this risk.

Keywords:
LUMBAR syndromelumbosacral infantile hemangiomasegmental infantile hemangioma

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Area of Science:

  • Dermatology
  • Pediatrics
  • Genetics

Background:

  • Infantile hemangiomas (IHs) are common vascular tumors in infants.
  • LUMBAR syndrome is a rare condition associated with specific patterns of IHs and anomalies.

Purpose of the Study:

  • To determine the specific characteristics of infantile hemangiomas associated with LUMBAR syndrome.
  • To refine risk stratification for LUMBAR syndrome based on IH morphology and location.

Main Methods:

  • Systematic review of clinical photographs from 91 patients diagnosed with LUMBAR syndrome.
  • Analysis of the morphology and anatomical location of infantile hemangiomas.

Main Results:

  • Infantile hemangiomas in LUMBAR syndrome patients were consistently segmental and involved the midline (lumbosacral, sacrococcygeal, or pelvic regions).
  • No cases showed partial segmental involvement or spared the midline; hemangiomas were transmedian in almost all patients.
  • One patient had a unilateral, paramedian hemangioma abutting the midline.

Conclusions:

  • Segmental infantile hemangiomas involving the anatomic midline are strong indicators of LUMBAR syndrome risk.
  • Strictly lateral hemangiomas without midline involvement do not confer risk for LUMBAR syndrome.
  • This finding allows for improved clinical assessment and management strategies for infantile hemangiomas.