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Virtual Reality for Pain Management During Repeated Pediatric Laser Procedures: Protocol for a Pilot Randomized

Megan Armstrong^1,2, Hannah Williams^1,2, Esteban Fernandez Faith^3,4

¹Center for Injury Research and Policy, Abigail Wexner Research Institute, Nationwide Children's Hospital, 700 Children's Drive, RB3, Columbus, OH, 43205, United States, 1 614-355-5890.

JMIR Research Protocols

|June 9, 2026

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Virtual reality pain alleviation therapeutic (VR-PAT) shows promise in reducing pain and anxiety during laser procedures for pediatric patients. This study provides early evidence for VR-PAT

Area of Science:

Medical technology and pain management
Pediatric healthcare innovations

Background:

Laser procedures in medicine often cause pain and anxiety, especially in children.
Current pain mitigation methods like topical anesthetics and distraction techniques have limitations.
Virtual reality (VR) is a potential tool for managing procedural pain and anxiety.

Purpose of the Study:

To assess the safety, feasibility, and efficacy of the virtual reality pain alleviation therapeutic (VR-PAT).
To evaluate VR-PAT for pain management during outpatient laser procedures in pediatric patients.

Main Methods:

A crossover randomized clinical trial involving 40 pediatric patients undergoing outpatient laser therapy.
Participants used VR-PAT or a dark screen headset during laser sessions in a crossover design.

Keywords:

CO PDL VR anxiety dermatology distraction laser pain pediatric pulsed dye laser virtual reality

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Pain, anxiety, and medication usage were assessed using validated scales; simulator sickness was also monitored.

Main Results:

Data collection completed with 40 participants (ages 6-21) finishing both intervention and control sessions.
The sample was balanced, with 22 females (55%).
Data analysis is ongoing, with final results anticipated in June 2026.

Conclusions:

This trial will offer initial evidence on VR-PAT's effectiveness in reducing pain and anxiety during laser procedures.
Findings are expected to guide future large-scale, multi-site studies on VR-PAT efficacy.