Early Experience With Utilizing Biodegradable Temporizing Matrix (BTM) for Complex Pediatric Wound Reconstruction

Area of Science:

• Pediatric Surgery
• Wound Healing
• Regenerative Medicine

Background:

• Biodegradable Temporizing Matrix (BTM) is a synthetic dermal regeneration template.
• Established in adult burn care, BTM use in pediatric complex wounds is emerging.
• This case series details early institutional experience with BTM in pediatric wound management.

Purpose of the Study:

• To evaluate the efficacy and outcomes of BTM for complex pediatric wounds.
• To identify potential complications and learning points for BTM application in children.
• To assess BTM's role as a reconstructive option in pediatric wound care.

Main Methods:

• Retrospective chart review at Alberta Children's Hospital.
• Inclusion of 11 pediatric patients (2 weeks to 15 years) treated with BTM.
• Data collection on wound etiology, BTM rationale, size, closure time, complications, and outcomes.

Main Results:

• BTM used for diverse pediatric wounds (trauma, infection, pressure, postsurgical), including those with sepsis or exposed structures.
• One treatment failure due to patient removal of BTM.
• 6 patients received split-thickness skin grafts (STSG) post-BTM; 5 healed by secondary intention.
• Wound colonization was the most common complication, managed successfully with oral antibiotics.

Conclusions:

• BTM is a valuable reconstructive tool for challenging pediatric wounds.
• Its application and optimal placement on the reconstructive ladder are still evolving.
• Key learning points for pediatric BTM use are presented.