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Surgery for Superior Sulcus Tumor, Partially Using a Robotic Approach, After Neoadjuvant Nivolumab With
Hitoshi Igai1, Akinobu Ida1, Kazuki Numajiri1
1Department of General Thoracic Surgery, Japanese Red Cross Maebashi Hospital, Maebashi, Japan.
Neoadjuvant immunochemotherapy combined with robotic surgery offers a promising approach for superior sulcus tumors. This hybrid surgical technique improved prognosis and limited complications, leading to a major pathologic response.
Area of Science:
- Thoracic oncology
- Surgical innovation
- Immunotherapy
Background:
- Superior sulcus tumors traditionally treated with chemoradiotherapy and surgery.
- Radiation-induced fibrosis complicates surgical resection.
- Neoadjuvant nivolumab plus chemotherapy shows improved prognosis and fewer surgical complications.
Purpose of the Study:
- To report a case of superior sulcus tumor managed with neoadjuvant immunochemotherapy and a hybrid surgical approach.
- To evaluate the feasibility and outcomes of robotic-assisted surgery in this context.
Main Methods:
- A hybrid surgical approach combining an L-shaped incision for chest wall resection.
- Robotic-assisted left upper lobectomy and lymphadenectomy.
- Preoperative treatment with neoadjuvant nivolumab and platinum-based chemotherapy.
Main Results:
- Successful surgical resection of the superior sulcus tumor was achieved.
- The patient experienced a major pathologic response.
- The recovery was uneventful, with limited perioperative complications.
Conclusions:
- Neoadjuvant immunochemotherapy followed by robotic-assisted surgery is a viable strategy for superior sulcus tumors.
- This combined approach can optimize patient outcomes and surgical management.
- Further research is warranted to validate these findings in larger cohorts.
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