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Nontraumatic Spinal Cord Injury Etiology and Rehabilitation Outcomes: SCI Model Systems Pilot Study Data
Ronald K Reeves1, Yuying Chen2, Yue Zhang2
1Mayo Clinic College of Medicine, Rochester, Minnesota.
Topics in Spinal Cord Injury Rehabilitation
|April 24, 2026
Summary
Researchers studied nontraumatic spinal cord injury (NTSCI) demographics and rehabilitation outcomes. The Spinal Cord Injury Model Systems (SCIMS) pilot cohort shows NTSCI is common in older adults and diverse etiologies impact outcomes.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Epidemiology
Background:
- The Spinal Cord Injury Model Systems (SCIMS) has historically focused on traumatic spinal cord injury (TSCI).
- Pilot funding enabled the initial study of individuals with nontraumatic spinal cord injury (NTSCI) within the SCIMS program.
- This research addresses a gap in understanding NTSCI, which differs significantly from TSCI.
Purpose of the Study:
- To characterize the demographic profile of the NTSCI pilot cohort.
- To identify the etiological causes of NTSCI in the study population.
- To describe inpatient rehabilitation outcomes for individuals with NTSCI.
Main Methods:
- A descriptive study design was employed.
- Adults with NTSCI admitted to SCIMS centers were included.
- Data were collected via medical records abstraction and survey questionnaires.
Main Results:
- 187 individuals with NTSCI participated.
- Common etiologies included degenerative vertebral causes (n=67), tumor-malignant (n=29), and vascular (n=28).
- The average age was 59.2 years, with over 40% aged 60-74. The population was 35% female, predominantly non-Hispanic White (59.5%).
Conclusions:
- The US SCIMS program can successfully recruit NTSCI research participants.
- Ongoing NTSCI research within SCIMS can yield valuable data comparable to TSCI research.
- This study establishes a foundation for future NTSCI research and intervention development.
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