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Ligation Versus Repair of Isolated Traumatic Peripheral Venous Injury: A Systematic Review and Meta-Analysis
Noman Shahzad1, Muhammad Asad Moosa2, Nadeem Ahmed Siddiqui3
1Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust, Doncaster, United Kingdom.
Annals of Vascular Diseases
|April 24, 2026
Summary
For traumatic deep venous injuries, surgical ligation is linked to increased amputation and mortality rates compared to venous repair. Repair is favored over ligation for better patient outcomes in trauma care.
Area of Science:
- Vascular Surgery
- Trauma Management
- Evidence-Based Medicine
Background:
- Management guidelines for traumatic deep venous injuries are lacking.
- Reconstruction versus ligation is a critical decision in treating venous injuries.
Purpose of the Study:
- To compare outcomes of venous reconstruction versus ligation in isolated traumatic venous injuries.
- To evaluate the impact of surgical approach on mortality, amputation, and other complications.
Main Methods:
- Systematic review and meta-analysis of observational studies (1950-2020).
- Searched PubMed, Google Scholar, Cochrane, and Web of Science databases.
- Followed PRISMA guidelines for study selection and synthesis.
Main Results:
- Ligation significantly increases amputation rates (OR=1.73) and mortality (OR=1.50).
- No significant differences were found in chronic venous insufficiency, deep vein thrombosis, or pulmonary embolism rates.
- Insufficient data exists for detailed analysis of repair techniques or clinical severity.
Conclusions:
- Evidence favors venous repair over ligation for isolated traumatic venous injuries.
- Repair is associated with reduced rates of amputation and mortality.
- Further research is needed to analyze specific repair methods and patient factors.
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