Syncope Associated With Alternating Fascicular Block in an Elderly Woman: A Case Report
Francesca Cali1, Goitom Weldearegay2, Chris Sani2
1Internal Medicine, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Insights
Alternating fascicular block (AFB) can indicate serious heart conduction disease, often causing syncope. Early pacemaker implantation is recommended for symptomatic patients, even without explicit guidelines.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Case Reports
Background:
- Alternating fascicular block (AFB) involves intermittent left anterior and posterior fascicular blocks on ECG.
- While alternating bundle branch block is a recognized high-risk abnormality, evidence for AFB is less clear.
- AFB can signify advanced infra-Hisian conduction disease, potentially leading to syncope and bradyarrhythmias.
Abstract:
Alternating fascicular block (AFB) is defined by intermittent left anterior fascicular block and left posterior fascicular block on serial electrocardiograms. Although alternating bundle branch block is well recognized as a high‑risk conduction abnormality warranting permanent pacing, evidence and guideline clarity for AFB remain limited. This case describes an 81‑year‑old woman with recurrent syncope. AFB was found on EKG, and a permanent pacemaker was introduced. AFBs are a supporting marker of advanced infra‑Hisian conduction disease and can be associated with syncope and clinically significant bradyarrhythmias. In symptomatic patients, early consideration of permanent pacing is reasonable despite the absence of explicit guideline recommendations. This case highlights key diagnostic features and management considerations while underscoring the need for clearer evidence-based guidance regarding AFB.
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