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Updated: Apr 25, 2026
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Published on: September 5, 2017
Revealing Hidden Nodal Disease: FDG PET/CT Driven Detection of Occult Lymph Node Involvement in Blastic Plasmacytoid
Nivedita Kundu1, Jagatti Krishna1, Rakesh Kumar1
1Departments of Nuclear Medicine.
Abstract:
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive malignancy characterized by skin involvement and frequent systemic dissemination. We report a case of a 32-year-old man with multiple violaceous cutaneous nodules who underwent F-18 FDG PET/CT for staging. PET/CT demonstrated extensive metabolic activity in cutaneous sites and revealed previously unsuspected inguinal and cervical lymph-node involvement. Histopathology confirmed BPDCN. This case highlights the crucial role of FDG PET/CT in detecting subclinical nodal disease, delineating total disease burden, and improving staging accuracy in BPDCN, thereby supporting its value in guiding management and future response assessment.
