Coupled Orientational Disorder and Hydrogen-Bond Destabilization Drive Anisotropic Surface Melting in Curcumin

Artem Shagurin1,2,3, Michael G Kiselev3, Pal Jedlovszky4

  • 1University of Lille, CNRS UMR 8516 -LASIRe - Laboratoire Avancé de Spectroscopie pour les Interactions la Réactivité et l'environnement, 59000 Lille, France.

Summary

Molecular crystal surface stability is polymorph-dependent. This study reveals anisotropic interfacial softening in curcumin polymorphs, driven by face-specific molecular rearrangements and intermolecular forces.

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