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Updated: Apr 26, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
Published on: March 8, 2019
Design of Low-Wear and Self-Recoverable Polyurethane Elastomers via Microphase Separation and Dynamic Bonding for
Shiyu Cao1, Chenchen Wang1, Qike Gao2
1School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China.
None:
High-performance materials for artificial meniscus prostheses currently exhibit notable limitations in wear resistance, failing to fully adapt to the complex physiological microenvironment of the human body. Polyurethane elastomers have emerged as highly promising candidate materials in the biomedical field, attributed to their tunable mechanical properties and facile processability. In this study, a low-wear, self-healing polyurethane elastomer (PPU1.0) for artificial meniscus prostheses is developed through the synergistic optimization of microphase separation and dynamic hydrazone bonds. PPU1.0 achieved significantly reduced friction, with an average coefficient of friction (ACOF) of 0.06578, alongside rapid self-recovery performance through precisely controlling the isocyanate index (R = 4.5) and the density of the hydrazone bond derived from perillaldehyde.

