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Published on: October 4, 2021
Impulse control disorders and dopamine agonists
Ross Hamblin1, Georgia Ntali2, Niki Karavitaki2
1Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom; Department of Endocrinology and Diabetes, Southmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom.
Dopamine agonists (DAs) may increase impulse control disorder (ICD) risk in prolactinoma patients. This review examines DA-associated ICD prevalence, variability, and clinical management strategies for pituitary tumor patients.
Area of Science:
- Neuroendocrinology
- Behavioral Science
Background:
- Impulse control disorders (ICDs) are linked to dopamine agonist (DA) medications.
- DAs are frequently prescribed for prolactinoma, a common pituitary tumor.
Purpose of the Study:
- To review the prevalence of ICDs in pituitary tumor patients.
- To evaluate the association between DAs and ICDs.
- To outline clinical management and identify research gaps.
Main Methods:
- Narrative review of existing literature.
- Analysis of studies on ICD prevalence in pituitary tumor patients.
- Appraisal of evidence linking DAs to ICDs.
Main Results:
- Significant association noted between DA use and ICDs.
- Variability in reported ICD prevalence exists.
- Evidence supports a link, but further research is needed.
Conclusions:
- DA treatment for prolactinoma may elevate ICD risk.
- Clinical vigilance and further research are crucial for managing DA-associated ICDs.
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