Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

1.0K
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inverse Association between the ω-3 Index and Neutrophil-Lymphocyte Ratio: Pooled Results from Four Supplementation Trials.

The Journal of nutrition·2026
Same author

Association of physical function and sleep with oxidative stress in adults with chronic pain: A pragmatic clinical trial secondary analysis.

The Journal of international medical research·2026
Same author

CYP gene variants show preliminary evidence of association with patient-reported outcomes in active-duty service members with chronic pain.

Molecular pain·2026
Same author

Omega-6 polyunsaturated fatty acids and adiposity in the UK Biobank Cohort: a cross-sectional and longitudinal prospective analysis.

The British journal of nutrition·2026
Same author

A combined progressive muscle relaxation and walking intervention for adults with end-stage kidney disease receiving hemodialysis (<i>Fight Fatigue</i>): Study development and protocol.

Contemporary clinical trials communications·2026
Same author

Circulating saturated fatty acids and incident chronic kidney disease: a meta-analysis of de-novo prospective cohort investigations.

The American journal of clinical nutrition·2026

Related Experiment Video

Updated: May 5, 2026

A Tactile Automated Passive-Finger Stimulator TAPS
19:44

A Tactile Automated Passive-Finger Stimulator TAPS

Published on: June 3, 2009

14.9K

Latent profile analysis for the IPQ-R: Practical analysis recommendations informed by simulation.

Jason Westra1, Nathan Tintle1, Eleanor Rivera1

  • 1University of Illinois Chicago, IL, USA.

Journal of Health Psychology
|April 26, 2026
PubMed
Summary
This summary is machine-generated.

Latent profile analysis (LPA) shows adequate performance for the Revised Illness Perception Questionnaire (IPQ-R) with sample sizes of 100 or more. However, subgroup differences and sample heterogeneity significantly impact accuracy, requiring careful consideration for reliable results.

Keywords:
cluster analysisillness perceptionslatent profile analysisstatistical methods

More Related Videos

Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control
08:37

Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control

Published on: March 30, 2015

13.8K
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

3.2K

Related Experiment Videos

Last Updated: May 5, 2026

A Tactile Automated Passive-Finger Stimulator TAPS
19:44

A Tactile Automated Passive-Finger Stimulator TAPS

Published on: June 3, 2009

14.9K
Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control
08:37

Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control

Published on: March 30, 2015

13.8K
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

3.2K

Area of Science:

  • Psychometrics
  • Statistical Modeling
  • Health Psychology

Background:

  • Latent profile analysis (LPA) is an emerging statistical technique.
  • The Revised Illness Perception Questionnaire (IPQ-R) is a common tool for assessing illness perceptions.
  • Integrating LPA with IPQ-R data requires understanding methodological considerations.

Purpose of the Study:

  • To provide guidance for researchers using LPA with IPQ-R data.
  • To evaluate the performance of LPA under various simulated conditions.
  • To offer recommendations for sample size and heterogeneity when applying LPA to IPQ-R.

Main Methods:

  • Utilized simulated datasets to explore 640 parameters.
  • Varied sample size, IPQ-R distribution, covariance, and subscale means.
  • Simulated 3 distinct latent subgroups using the MClust package in R.

Main Results:

  • LPA performance is inadequate with sample sizes below 100 (detection <50%).
  • Sample sizes of 100 or greater may still yield suboptimal results based on subgroup sizes and within-group variance.
  • Increased differences between subgroups enhance LPA accuracy.

Conclusions:

  • Researchers should exercise caution with sample sizes under 100 when using LPA for IPQ-R.
  • Sample heterogeneity and subgroup characteristics are critical factors influencing LPA accuracy.
  • Careful estimation of sample size based on anticipated heterogeneity is crucial for robust LPA findings with IPQ-R data.