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Updated: Apr 28, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Establishing Glycemic Targets: Epidemiologic Insights and Landmark Studies in Hospital Management
Diana Soliman1, Ron T Varghese2, Guillermo E Umpierrez3
1Division of Endocrinology, Department of Internal Medicine, University of Miami Miller School of Medicine, 1450 Northwest 10th Avenue, Miami, FL 33136, USA.
Abstract:
Dysglycemia in hospitalized patients, including hyperglycemia, hypoglycemia, and glycemic variability, is associated with adverse clinical outcomes and increased health care utilization. Evidence from landmark trials in critically ill patients supports moderate glycemic targets (140-180 mg/dL) over intensive control. Basal-bolus regimens improve outcomes compared to sliding scale insulin alone in noncritically ill settings. However, limited studies have compared glycemic targets in the noncritically ill hospitalized population. Emerging data support the use of continuous glucose monitoring and diabetes technology in the inpatient setting. Current guidelines emphasize individualized and protocol-driven management to optimize inpatient care.
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