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Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
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Associations Between Avoidant/Restrictive Food Intake Disorder Dimensions and Obsessive-Compulsive Symptomatology.

Mariana Valdez Aguilar1, Gabriela K Giulumian1,2, Isabel Rodriguez1,3

  • 1Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

European Eating Disorders Review : the Journal of the Eating Disorders Association
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PubMed
Summary
This summary is machine-generated.

Avoidant/Restrictive Food Intake Disorder (ARFID) dimensions are linked to obsessive-compulsive disorder (OCD) symptoms. These associations differ by sex, even after accounting for depression and anxiety.

Keywords:
anxietydepressioneating disordersfeeding disordersobsessive‐compulsive symptomatology

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neuroscience

Background:

  • Obsessive-compulsive disorder (OCD) frequently co-occurs with eating disorders like anorexia nervosa and bulimia nervosa.
  • The relationship between OCD and avoidant/restrictive food intake disorder (ARFID) dimensions is less understood.
  • Differences in ARFID-OCD associations based on sex remain unclear.

Purpose of the Study:

  • To investigate the associations between ARFID dimensions and OCD symptoms.
  • To determine if these associations vary by sex.
  • To control for the influence of depression and anxiety on these relationships.

Main Methods:

  • Analysis of data from 3120 participants aged 15+ in the ARFID Genes and Environment (ARFID-GEN) study.
  • Assessment of ARFID dimensions (sensory sensitivity, low appetite, fear of consequences), OCD symptoms, anxiety, and depression using validated self-report measures.
  • Evaluation of associations using general linear models, adjusted for depression and anxiety.

Main Results:

  • Significant associations were found between ARFID dimensions and OCD symptoms.
  • These associations remained significant after adjusting for depression and anxiety, though attenuated.
  • The relationship between ARFID dimensions and OCD symptoms demonstrated variation by sex.

Conclusions:

  • Further research is needed to explore the ARFID-OCD relationship across developmental stages.
  • Bidirectional screening may enhance diagnostic clarity for ARFID and OCD.
  • Tailoring interventions based on screening results could improve treatment outcomes.