Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Methods of Documentation VII: EMR01:30

Methods of Documentation VII: EMR

1.5K
Electronic Medical Records (EMRs) primarily center around electronically documenting patients' health information within a single healthcare organization or practice. They contain essential clinical data related to a patient's medical history, diagnoses, medications, treatment plans, lab results, and other pertinent information relevant to the specific encounter or episode of care. EMRs are designed to streamline documentation and workflow processes within individual healthcare...
1.5K
Multimachine Stability01:25

Multimachine Stability

677
Multimachine stability analysis is crucial for understanding the dynamics and stability of power systems with multiple synchronous machines. The objective is to solve the swing equations for a network of M machines connected to an N-bus power system.
In analyzing the system, the nodal equations represent the relationship between bus voltages, machine voltages, and machine currents. The nodal equation is given by:
677

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

How can biological databases support the new UN mechanism for benefit-sharing from digital sequence information?

Scientific data·2026
Same author

From "synthetic" to defined microbial communities for clearer terminology.

Nature communications·2026
Same author

Gut microbiome community structure correlates with different behavioral phenotypes in the Belyaev Farm-Fox Experiment.

Communications biology·2026
Same author

nf-core/proteinfamilies: a scalable pipeline for the generation of protein families.

GigaScience·2026
Same author

Induction of menstruation in mice reveals the regulation of menstrual shedding.

bioRxiv : the preprint server for biology·2025
Same author

Ensembl 2026.

Nucleic acids research·2025
Same journal

MAPK/ERK signaling regulates H3K9me3 heterochromatin reorganization to confer mesendoderm developmental competence.

Nucleic acids research·2026
Same journal

Antibody-trapping presents a widespread pitfall for microscopy and genomics in the nucleus.

Nucleic acids research·2026
Same journal

Dosage compensation defects due to roX RNA loss are rescued by recalibration of X/autosome stoichiometry.

Nucleic acids research·2026
Same journal

RNA G-quadruplexes function as a tunable switch of FUS phase separation.

Nucleic acids research·2026
Same journal

Persistence of large mtDNA rearrangements linked to premature aging in Pol γ exonuclease-deficient mice.

Nucleic acids research·2026
Same journal

Transcriptional interference drives intronic polyadenylation at the endogenous H13/Mcts2 locus.

Nucleic acids research·2026
See all related articles
  1. Home
  3. Hmmer Web Server: 2026 Update.
  1. Home
  3. Hmmer Web Server: 2026 Update.

Related Experiment Video

gP2S, an Information Management System for CryoEM Experiments
13:01

gP2S, an Information Management System for CryoEM Experiments

Published on: June 10, 2021

5.3K

HMMER web server: 2026 update.

Aleksandar Rajković1, Martin Beracochea1, Alexander B Rogers1

  • 1EMBL-EBI European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.

Nucleic Acids Research
|April 27, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

The HMMER web server has been updated with a reengineered interface and infrastructure to improve protein analysis performance and reliability. It now offers enhanced user experience and better support for large-scale sequence similarity searches and annotations.

More Related Videos

The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm
06:18

The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm

Published on: October 20, 2022

2.3K
Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline
11:09

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline

Published on: January 5, 2017

16.6K

Related Experiment Videos

gP2S, an Information Management System for CryoEM Experiments
13:01

gP2S, an Information Management System for CryoEM Experiments

Published on: June 10, 2021

5.3K
The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm
06:18

The Collective Trust Game: An Online Group Adaptation of the Trust Game Based on the HoneyComb Paradigm

Published on: October 20, 2022

2.3K
Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline
11:09

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline

Published on: January 5, 2017

16.6K

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • The HMMER web server provides access to the HMMER software suite for protein analysis using profile hidden Markov models.
  • Exponential growth in sequence databases necessitates infrastructure improvements for performance and reliability.

Purpose of the Study:

  • To reengineer the HMMER web server for enhanced user experience and improved performance.
  • To support programmatic access and efficient handling of large-scale database searches.

Main Methods:

  • Complete reengineering of the web interface using modern web technologies (JavaScript, React).
  • Rewriting the web application programming interface (API) with updated endpoints and JSON responses.
  • Redesigning the infrastructure for horizontal scaling and asynchronous job processing.

Main Results:

  • Enhanced user experience with session-based search history and streamlined results visualization.
  • Improved programmatic access via a rewritten API.
  • Efficient handling of searches against significantly larger databases.

Conclusions:

  • The updated HMMER web server offers a more robust and user-friendly platform for protein sequence analysis.
  • The improvements ensure continued service reliability and performance speed despite growing data volumes.
  • The server remains free and open to all users without login requirements.