Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

1.9K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.9K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

3.5K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
3.5K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.7K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.7K
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

96
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
96

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic and therapeutic impact of PCR in uveitis: real-world data from intraocular fluid analysis of 45 uveitis patients in a tertiary referral center in Turkey.

BMC ophthalmology·2026
Same author

Rifampicin-Associated DRESS Syndrome Followed by Rifabutin-Associated Hypopyon Uveitis in an Immunocompetent Patient with Mycobacterium Kansasii Infection.

Ocular immunology and inflammation·2026
Same author

Exploring clinical determinants and machine learning-based prediction of disease characteristics in Graves ophthalmopathy.

Clinical & experimental optometry·2026
Same author

Baseline OCT biomarkers associated with visual prognosis in cystoid macular edema secondary to noninfectious uveitis.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Neuro-Behçet's Syndrome Developing During Follow-Up for Behçet Uveitis: A Tertiary Uveitis Center Experience.

Ocular immunology and inflammation·2026
Same author

Long-Term Efficacy and Safety of Adalimumab in Pediatric Non-Infectious Uveitis: Including Weekly Dosing Escalation in Refractory Cases.

Ocular immunology and inflammation·2026

Related Experiment Video

Updated: Apr 28, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
09:54

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Published on: December 3, 2019

9.3K

Syphilitic Uveitis in HIV-Positive and -Negative Patients: A Multicenter Cohort Study.

Kübra Özdemir Yalçınsoy1, Murat Oklar2, Merve İnanç Tekin1

  • 1University of Health Sciences Türkiye, Ulucanlar Eye Training and Research Hospital, Clinic of Ophthalmology, Ankara, Türkiye.

Turkish Journal of Ophthalmology
|April 27, 2026
PubMed
Summary

Syphilitic uveitis presents diverse ocular symptoms. While human immunodeficiency virus (HIV) co-infection increases severe inflammation like panuveitis and optic nerve issues, it does not impact final vision outcomes.

Keywords:
HIVSyphilisocular syphilissyphilitic uveitistreatment

More Related Videos

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
13:50

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Published on: June 11, 2011

11.7K
Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
07:10

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies

Published on: January 7, 2019

14.1K

Related Experiment Videos

Last Updated: Apr 28, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
09:54

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Published on: December 3, 2019

9.3K
Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
13:50

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients

Published on: June 11, 2011

11.7K
Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
07:10

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies

Published on: January 7, 2019

14.1K

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Immunology

Background:

  • Syphilitic uveitis is a significant ocular manifestation of syphilis.
  • Clinical presentations and visual outcomes can vary, potentially influenced by co-infections.

Purpose of the Study:

  • To evaluate clinical manifestations and visual outcomes in syphilitic uveitis.
  • To compare these features between patients with and without human immunodeficiency virus (HIV) co-infection.

Main Methods:

  • Retrospective analysis of 33 patients diagnosed with syphilitic uveitis (2014-2024).
  • Data collected included demographics, ocular findings, serology, lumbar puncture results, treatment, and visual acuity.
  • Statistical analysis compared features based on HIV co-infection status.

Main Results:

  • Panuveitis (63%) and posterior uveitis (31%) were most common.
  • HIV co-infection (39%) was associated with higher rates of anterior segment inflammation and optic nerve involvement.
  • All patients showed significant visual acuity improvement post-treatment with penicillin.

Conclusions:

  • Syphilitic uveitis exhibits a wide range of ocular manifestations.
  • HIV co-infection is linked to more severe intraocular inflammation but does not affect final visual acuity or complication rates.