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Denys-Drash Syndrome by WT1 Gene: Clinical Variability and Management Challenges in Two Saudi Infants

Waleed Al-Amoudi1, Raghad Alhuthil2, Abdulrahman Alnwiji1

  • 1College of Medicine, Alfaisal University, Riyadh, Saudi Arabia, alfaisal.edu.

Case Reports in Endocrinology
|April 27, 2026
PubMed
Summary

Denys-Drash syndrome (DDS) is a rare genetic disorder affecting children. Early diagnosis and multidisciplinary care are crucial for managing WT1 gene mutations and improving outcomes in affected individuals.

Keywords:
Denys-Drash syndromeWT1 geneWilms tumorambiguous genitalia

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