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Current Options and Future Perspectives for Conversion Coatings on Biodegradable Magnesium Alloys to Control the
Veronica Manescu Paltanea1,2, Aurora Antoniac1, Julietta V Rau3,4
1Faculty of Material Science and Engineering, National University of Science and Technology Politehnica Bucharest, 313 Splaiul Independentei, District 6, RO-060042 Bucharest, Romania.
Biomimetics (Basel, Switzerland)
|April 27, 2026
Summary
Conversion coatings enhance magnesium (Mg) alloys, controlling corrosion and improving biocompatibility for temporary implants. These surface modifications are crucial for clinical translation of Mg-based biodegradable metals.
Area of Science:
- Biomaterials Science
- Materials Engineering
- Surface Chemistry
Background:
- Magnesium (Mg)-based alloys are promising biodegradable metals for temporary implants.
- High corrosion rates in physiological environments limit their clinical application.
- Conversion coatings offer a strategy to mitigate corrosion and enhance biocompatibility.
Purpose of the Study:
- To review various conversion coating techniques for Mg-based alloys.
- To analyze the impact of these coatings on corrosion and biological response.
- To explore their role in angiogenic and osteogenic signaling pathways.
Main Methods:
- Comprehensive literature review of conversion coating techniques.
- Analysis of corrosion behavior and parameters.
- Evaluation of biological responses, including bioactivity and biocompatibility.
- Assessment of cellular signaling pathways (angiogenic and osteogenic).
Main Results:
- Various conversion coatings (ceramic, polymeric, bioactive, hybrid) were analyzed.
- Coatings demonstrate potential in controlling Mg alloy corrosion.
- Conversion coatings influence bioactivity, biocompatibility, and cellular responses.
- Specific angiogenic and osteogenic pathways are modulated by different coating types.
Conclusions:
- Conversion coatings significantly enhance Mg-based alloy surfaces for biomedical applications.
- Challenges remain in synchronizing Mg alloy degradation with bone regeneration.
- Further research is needed to precisely guide cell signaling for optimal biological outcomes.
- Conversion coatings are vital for the clinical translation of Mg-based biodegradable implants.
Keywords:
Mg-based alloysbioactive coatingsbiological responsecellular signaling pathwaysceramic coatingsconversion coatingscorrosion behaviorhybrid coatingspolymeric coatingsMore Related Videos
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