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Updated: Apr 28, 2026

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
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Emerging Trends in Chitin-Based Hydrogels: From Fundamental Properties to Advanced Applications.

Merreta Noorenza Biutty1, Ratri Puspita Wardani2, Zeno Rizqi Ramadhan3

  • 1Department of Chemical Engineering, Faculty of Industrial Engineering, Universitas Pembangunan Nasional "Veteran" Yogyakarta, Yogyakarta 55283, Indonesia.

Gels (Basel, Switzerland)
|April 27, 2026
PubMed
Summary

Chitin-based hydrogels offer sustainable solutions for biomedical and environmental needs. Advances in their design enhance properties for applications in drug delivery, tissue engineering, and energy devices.

Keywords:
biodegradable materialschitinhydrogelsstimuli-responsive materialssustainable materials

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Area of Science:

  • Materials Science
  • Biotechnology
  • Polymer Chemistry

Background:

  • Chitin-derived hydrogels are sustainable materials with tunable properties.
  • They offer biocompatibility and biodegradability for diverse applications.

Purpose of the Study:

  • To review recent advances in chitin-based hydrogel development.
  • To highlight key applications and future research directions.

Main Methods:

  • Focus on solvent systems, crosslinking strategies, and structural modifications.
  • Incorporation of nanoparticles and chemical derivatization.

Main Results:

  • Enhanced mechanical strength, swelling, and stimuli responsiveness achieved.
  • Successful applications in wound healing, drug delivery, tissue engineering, and environmental remediation.

Conclusions:

  • Chitin-based hydrogels show significant potential across multiple fields.
  • Further research needed to optimize energy efficiency for industrial scalability.