Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Information Processing Approach01:30

Information Processing Approach

882
The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
882
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

914
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
914
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

1.4K
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.4K
Operant Conditioning Intervention01:24

Operant Conditioning Intervention

725
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
725

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Undetectable Hydroxyurea Levels in the Majority of Sickle Cell Disease Patients, Especially in Young Children.

American journal of hematology·2026
Same author

Avoidant/Restrictive Food Intake Disorder and Food Neophobia in Adult Patients with Food Allergy: A Preliminary Study.

Nutrients·2026
Same author

Unheard and Under-Supported: Health-Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease.

Pediatric blood & cancer·2026
Same author

Quality of Life, Mental Health, and Illness Perception in Pediatric Food Allergy.

Children (Basel, Switzerland)·2025
Same author

A Combination of Plerixafor and Filgrasting Promotes Successful CD34+ Cell Collection for CRISPR/Cas9 Therapy in Sickle Cell Disease Patients With Insufficient Response to Plerixafor Alone.

American journal of hematology·2025
Same author

International variations in body mass index within the CASiRe global cohort of sickle cell disease patients.

Journal of sickle cell disease·2025

Related Experiment Video

Updated: Apr 28, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

6.8K

Using Coding to Improve Executive Functioning in Children with Sickle Cell Disease: A Multiple-Baseline Single-Case

Barbara Arfé1,2, Maria Elisa Delle Fave3, Chiara Montuori1

  • 1Department of Developmental Psychology and Socialization, University of Padova, 35131 Padova, Italy.

Journal of Intelligence
|April 27, 2026
PubMed
Summary

This study shows that coding activities can help children with sickle cell disease improve executive functions (EFs). The problem-solving approach was feasible and beneficial for children facing cognitive challenges.

Keywords:
codingcognitive trainingcomputational thinkingdevelopmental disabilitiesexecutive functionssickle-cell disease

More Related Videos

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

5.4K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

3.0K

Related Experiment Videos

Last Updated: Apr 28, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

6.8K
The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

5.4K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy
07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

3.0K

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Pediatric Health

Background:

  • Executive function (EF) deficits are prevalent in children with intellectual and developmental disabilities, impacting learning and daily functioning.
  • Traditional cognitive training for EFs often lacks feasibility and generalization; ecological, curriculum-embedded problem-solving may be more effective.
  • Sickle cell disease is linked to cognitive decline and EF impairments, necessitating targeted interventions.

Purpose of the Study:

  • To assess the feasibility and efficacy of a brief, problem-solving-based computational thinking and coding intervention for children with sickle cell disease and EF impairments.
  • To evaluate the intervention's impact on non-verbal and verbal executive functions.

Main Methods:

  • A multiple-baseline single-case study design adhering to What Works Clearinghouse (WWC) Version 5 guidelines.
  • Three children (7-8 years old) with lower-range IQ and EF deficits participated in 11 coding sessions using code.org over 5-6 weeks.
  • Pre/post assessments measured non-verbal EF (planning, inhibition, switching) and verbal EF (working memory, fluency).

Main Results:

  • 100% adherence to the coding intervention was observed.
  • Significant coding skill improvement (IRD range = 0.69-0.79) and positive transfer effects on non-verbal planning (gains > 2 z-scores) and verbal fluency (z-score gains 0.47-1.04) were found.
  • Inter-individual variability in outcomes correlated with individual cognitive profiles.

Conclusions:

  • Problem-solving, coding-based activities are feasible for children with sickle cell disease and significant EF impairments.
  • This intervention shows potential benefits for enhancing executive functions in this population.
  • Tailoring interventions to individual cognitive profiles may optimize outcomes.