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[Cutaneous Cryptococcus neoformans Infection Mimicking Necrotizing Fasciitis in a Myelofibrosis Patient Receiving
Tuba Kuruoğlu1, Tuba Sena Karaçeşme1, Sümeyye Ekmekçi Kurt1
1Ondokuz Mayıs University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Samsun, Türkiye.
Mikrobiyoloji Bulteni
|April 27, 2026
Summary
This case report details a rare instance of cutaneous cryptococcosis in a myelofibrosis patient on ruxolitinib therapy. The infection mimicked necrotizing fasciitis, highlighting the need for vigilance in immunosuppressed individuals.
Area of Science:
- Mycology
- Immunology
- Dermatology
Background:
- Cryptococcus neoformans is a critical-priority fungal pathogen causing high mortality.
- Cutaneous cryptococcosis is a rare manifestation, often indicating disseminated disease.
- Ruxolitinib, a JAK inhibitor, can predispose patients to opportunistic infections like cryptococcosis.
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