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Updated: Apr 28, 2026

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
Published on: September 2, 2025
HyKey: hyperspectral keypoint detection and matching in minimally invasive surgery
Alexander Saikia1,2,3, Chiara Di Vece4,5, Zhehua Mao4,5
1Department of Medical Physics and Biomedical Engineering, UCL Hawkes Institute, University College London, London, WC1E 6BT, UK. alexander.saikia.21@ucl.ac.uk.
Purpose:
3D reconstruction in minimally invasive surgery (MIS) enables enhanced surgical guidance through improved visualisation, tool tracking, and augmented reality. However, traditional RGB-based keypoint detection and matching pipelines struggle with surgical challenges, such as poor texture and complex illumination. We investigate whether using snapshot hyperspectral imaging (HSI) can provide improved results on keypoint detection and matching surgical scenes.
Methods:
We developed HyKey, a hyperspectral keypoint detection and description model made up of a hybrid 3D-2D convolutional neural network that jointly extracts spatial-spectral features from HSI. The model was trained using synthetic homographic augmentation and epipolar geometry constraints on a robotically acquired dual-camera RGB-HSI laparoscopic dataset of ex vivo organs with calibrated camera poses. We benchmarked performance against established RGB-based methods, including SuperPoint and ALIKE.
Results:
Our HSI-based model outperformed RGB baselines on registered RGB frames, achieving 96.62% mean matching accuracy and 67.18% mean average accuracy at 10 on pose estimation, demonstrating consistent improvements across multiple evaluation metrics.
Conclusion:
Integrating spectral information from an HSI cube offers a promising approach for robust monocular 3D reconstruction in MIS, addressing limitations of texture-poor surgical environments through enhanced spectral-spatial feature discrimination. Our model and dataset are available at https://github.com/alexsaikia/HyKey-Hyperspectral-Keypoint-Detection.
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