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pH-Dependent Luminescence of Flufenamic Acid Utilizing Molecular Logic Gate Operations
N C Prachalith1, K Vibha2, H M Suresh Kumar3
1Department of Allied Sciences, R.L. Jalappa Institute of Technology, Doddaballapura 561203, India.
Applied Spectroscopy
|April 28, 2026
Summary
Flufenamic acid (FFA) shows unique pH-dependent optical changes, enabling its use as a novel pH sensor. This research explores its potential in molecular logic gates and organic electronics.
Area of Science:
- Materials Science
- Chemistry
- Biochemistry
Background:
- Flufenamic acid (FFA) is a nonsteroidal anti-inflammatory drug.
- Its pH-dependent optical properties are largely unexplored for functional materials.
Purpose of the Study:
- Investigate FFA's pH-dependent optical behavior.
- Explore its application in molecular logic gates and organic electronics.
Main Methods:
- Systematic study of FFA's UV-Vis absorption and fluorescence spectra across a wide pH range (1-14).
- Construction of molecular logic gates using FFA's pH-responsive spectral changes.
Main Results:
- Distinct and reversible spectral changes observed due to protonation/deprotonation.
- Successful construction of implication and IP-INHIBIT molecular logic gates.
Conclusions:
- FFA exhibits potential as an on-off pH sensor.
- FFA is a promising candidate for organic electronic applications due to its pH-responsive optical characteristics.
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