Related Experiment Video
Updated: Apr 30, 2026

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Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
Published on: September 15, 2017
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An inflammation memento
1Science Signaling, AAAS, Washington, DC 20005, USA.
Science Signaling
|April 28, 2026
Summary
Colitis causes epigenetic alterations in colonic stem cells, predisposing them to develop tumors. These changes highlight a critical link between chronic inflammation and cancer initiation.
Area of Science:
- Gastroenterology and Oncology
- Epigenetics and Cancer Biology
Background:
- Colitis, a form of inflammatory bowel disease, is associated with an increased risk of colorectal cancer.
- Epigenetic modifications play a crucial role in the development of various cancers, including those arising from chronic inflammation.
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