Related Experiment Video
Updated: Apr 30, 2026

Tissue Targeted Embryonic Chimeras: Zebrafish Gastrula Cell Transplantation
Published on: September 11, 2009
From genes to germ layers: virtual twins of gastruloids
Leona M Irwin1, Shaun M Cowley1, Himanshu Kaul2,3
1Division of Molecular and Cell Biology, School of Biological and Biomedical Sciences, University of Leicester, Leicester, UK.
Abstract:
Human gastrulation remains a black box due to ethical and technical reasons. Human pluripotent stem cell-based 2D micropatterns and 3D organoids (gastruloids) recapitulate aspects of human gastrulation. Understanding the integrated multiscale biology of gastrulation, however, remains elusive. We explain the barriers to recapitulating the multiscale biology of gastrulation in silico, how agent-driven multi-paradigm approach can overcome these challenges, provide relevant examples, and share best practices on developing the virtual twins.
More Related Videos
Related Concept Videos
Gastrulation
What is Monogastric Digestion?
Gastric Motility
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
Gross Anatomy of the Stomach
Neurulation
Diversity of Protists I

