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Breathing through the night: A meta-analysis of childhood asthma and obstructive sleep apnea in sleep-disordered

Kaiwen Zheng1, Yuling Zhao2, Jiayi Li2

  • 1From the School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China and.

Allergy and Asthma Proceedings
|April 29, 2026
PubMed

Insights

Childhood asthma is significantly linked to a higher risk of obstructive sleep apnea (OSA). This association suggests sleep disorders may worsen asthma, warranting integrated screening and management.

Area of Science:

  • Pediatrics
  • Pulmonology
  • Sleep Medicine

Background:

  • Asthma is a common chronic respiratory disease in children.
  • Obstructive sleep apnea (OSA) is a prevalent sleep disorder in pediatric populations.
  • The relationship between childhood asthma and OSA requires systematic evaluation.

Purpose of the Study:

  • To systematically evaluate the correlation between childhood asthma and obstructive sleep apnea (OSA).

Main Methods:

  • A comprehensive literature search was conducted across multiple databases up to March 2025.
  • Keywords included "asthma," "obstructive sleep apnea," and "child*."
  • Included were observational studies with children diagnosed with OSA and asthma using established criteria.

Main Results:

  • Eleven studies from the US, Europe, and Asia were included.
  • A pooled odds ratio (OR) of 1.66 (95% CI, 1.21-2.26) indicated a significant association between childhood asthma and OSA.
  • The association was strongest in America and Asia, with significant findings in cohort and cross-sectional studies.

Conclusions:

  • Childhood asthma is significantly associated with an increased risk of OSA.
  • Sleep disorders may exacerbate the asthma condition.
  • Integrated screening and management strategies are recommended, especially in high-risk regions like America and Asia.

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