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Updated: Apr 30, 2026

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The Equity Deficit in Revascularization Research: Patient Perspectives Emphasize the Need for Inclusive,

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Patients from underrepresented groups prioritize quality of life and functional recovery. Findings from this study will improve recruitment and patient-centered cardiovascular research for diverse populations.

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Area of Science:

  • Cardiovascular Medicine
  • Health Equity
  • Qualitative Research

Background:

  • Clinical trials for coronary artery bypass grafting (CABG) vs. percutaneous coronary intervention (PCI) have historically excluded women and minority groups.
  • Traditional cardiovascular trial endpoints often overlook patient-centered outcomes like symptoms, function, and quality of life (QoL).
  • The RECHARGE trial aims to address these gaps by focusing on underrepresented populations and patient-reported outcomes.

Purpose of the Study:

  • To inform the patient-centered design of the RECHARGE trial.
  • To develop effective recruitment strategies for underrepresented groups in cardiovascular research.
  • To identify patient priorities regarding treatment decisions for cardiovascular disease.

Main Methods:

  • A prospective qualitative study involving 42 adults (ages 45-75) from Black and Hispanic communities with cardiovascular disease.
  • Conducted 13 focus groups and 11 individual interviews in English or Spanish.
  • Thematic analysis using directed content analysis until data saturation was achieved.

Main Results:

  • Participants expressed a limited understanding of cardiovascular disease and felt dismissed by providers.
  • Quality of life, independence, and functional recovery were prioritized in treatment decisions.
  • Concerns regarding clinical trial randomization were linked to mistrust and a need for culturally responsive communication.

Conclusions:

  • Underrepresented patient groups prioritize functional recovery and value trustworthy research engagement.
  • Findings underscore the importance of patient-centered and equity-focused strategies in cardiovascular research.
  • These insights directly informed the RECHARGE trial's inclusive recruitment and design.