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High-depth RNA-seq data to investigate gene regulation mediated by phase-variable DNA methyltransferases in serogroup
Alice Ascari1, Luke V Blakeway1, Michael P Jennings1
1Institute for Biomedicine and Glycomics, Griffith University, Gold Coast, Queensland, Australia.
Microbiology Resource Announcements
|April 29, 2026
Abstract:
Neisseria meningitidis is a leading cause of bacterial meningitis and septicemia. Here, we report high-depth RNA-seq for N. meningitidis serogroup B strains MC58, B6116/77, and M0579. These strains encode phase-variable DNA methyltransferases ModA11, ModA12, and ModD1, respectively, which act as global epigenetic regulators central to meningococcal pathogenicity.

