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Updated: May 1, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
Published on: August 14, 2018
Searching for Phylogenetic Networks
1Division of Invertebrate Zoology, American Museum of Natural History, New York, NY, USA. wheeler@amnh.org.
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Phylogenetic networks play an increasingly important role in the comparative analysis of many systems. These include studies of hybridization, linguistic exchange, bacterial and viral evolution, and the origins of zoonotic disease. Computationally, these problems present many NP-hard optimizations requiring heuristic procedures to generate useful results. Here, algorithmic approaches to generate heuristic solutions are discussed and recommendations for real-world use cases are presented for the phylogenetic graph search tool Phylogenetic Graph (PhyG).
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