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Updated: May 1, 2026
Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
Published on: February 23, 2020
Intraoperative motor evoked potentials (MEP) improvement predicts functional outcomes in intracranial surgery
Prasuna Velur1, Marvin Gong1, Gabriel Zada1
1Keck School of Medicine of USC, United States of America.
Objective:
Transcranial Motor Evoked Potentials (TcMEPs) evaluate the functional integrity of corticospinal tracts during neurosurgical procedures. Intraoperative MEP improvements tend to correlate with better postoperative neurological outcomes, in spinal surgeries. Literature is limited on intraoperative MEP improvements and postoperative outcomes in intracranial surgeries.
Methods:
In this case report, we present a thalamic cyst fenestration in the setting of a pilocytic astrocytoma.
Results:
Immediately post thalamic cyst fenestration, MEPs improved with stable stimulation parameters, anesthesia, and systemic factors. The postoperative motor exam showed an improvement.
Conclusions:
Intraoperative MEP improvement post thalamic cyst fenestration could be associated with better postoperative outcomes.
Significance:
Intraoperative MEP improvement in intracranial surgeries can help predict postoperative outcomes.
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