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Everyday and task-based cognition shape emotion regulation effectiveness in Parkinson's disease
Caroline Seton1, Carien M van Reekum2, Aileen K Ho1
1School of Psychology and Clinical Language Sciences, University of Reading, Reading, United Kingdom.
Parkinsonism & Related Disorders
|April 30, 2026
Summary
Cognitive functioning influences how emotion regulation strategies affect mental health in Parkinson's disease (PD). Functional cognition is key, while executive functions have a smaller role in this relationship.
Area of Science:
- Neuroscience
- Psychology
- Clinical Medicine
Background:
- Parkinson's disease (PD) often presents with co-occurring cognitive dysfunction and emotional symptoms.
- The interplay between cognitive function and emotion regulation (ER) in PD is not fully understood.
- ER strategy use may be influenced by cognitive abilities, impacting mental health outcomes.
Purpose of the Study:
- To investigate the association between executive functioning (EF), functional cognitive impairment (FCI), and mental health (anxiety, depression, wellbeing) in PD.
- To determine if ER strategies moderate these associations.
- To explore the differential impact of task-based EF versus self-reported FCI.
Main Methods:
- 103 individuals with PD completed executive functioning (EF) tasks and self-report measures for FCI, ER strategies, and mental health.
- Principal component analysis identified task-based EF components.
- Moderation analyses examined interactions between cognitive functioning and ER strategies on mental health.
Main Results:
- Greater FCI correlated with negative associations between certain ER strategies (Seeking Distractions, Ignoring) and wellbeing, and increased anxiety/depression with Ignoring.
- For individuals with better functional cognition, specific ER strategies (Withdrawal, Catastrophizing) linked to poorer wellbeing, while others (Putting into Perspective) linked to lower depression.
- Task-based EF (Executive and Inhibitory Control) showed nuanced effects, moderating the link between Ignoring and anxiety/depression. Higher Acceptance was linked to more anxiety with stronger Executive Control.
Conclusions:
- Cognitive functioning significantly moderates the impact of ER strategies on mental health in Parkinson's disease.
- Functional cognition demonstrated more consistent moderating effects compared to task-based EF.
- Findings help explain the heterogeneity of affective symptoms observed in PD patients.
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