From Symptoms to Solutions: A Clinical Approach to Pediatric Functional Urinary Disorders in Settings without...

This study emphasizes the value of a structured clinical approach in managing pediatric patients with functional lower urinary tract symptoms (LUTS). By utilizing standardized clinical assessment tools, we aimed to categorize the range of LUTS presentations. In many low-resource settings, access to urodynamic studies (UDSs) is often limited, unavailable, or delayed. This study assessed the feasibility and effectiveness of initiating treatment based on clinical evaluation alone prior to the availability of UDSs.

This prospective observational study was conducted at a tertiary care center from April 2018 to October 2021. Children up to 12 years presenting with LUTS without structural or neurological etiologies were included. Categorization of patients was done using a comprehensive evaluation of detailed history, clinical examination, laboratory tests, radiological investigations, and maintenance of voiding diary.

Of the 65 enrolled patients, 46 completed follow-ups and thus met the inclusion criteria (M:F = 1.4:1). Patients <4 years at the age of presentation were categorized as non-lower urinary tract dysfunction (non-LUTD) group (n = 23), and 15 patients within this group had vesicoureteral reflux (VUR) with varying urodynamic findings. The LUTD group (n = 23) presented with varied manifestations: overactive bladder (n = 12), detrusor sphincter dyssynergia (n = 4), detrusor overactivity (n = 3), and hypotonic bladder (n = 4). Patients with all categories showed good symptomatic improvement with the treatment planned according to clinical categorization. No relapses were observed during subsequent follow-up of 6 months to 1 year.

Functional voiding disorders affect toddlers as well as older children. A systematic clinical approach combining thorough evaluation, imaging, and clinical urodynamics can effectively manage pediatric LUTD in resource-limited settings. UDSs in such situations may be reserved for recalcitrant cases or in patients with risks of upper tract damage.