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Updated: May 4, 2026

Translating Ribosome Affinity Purification TRAP to Investigate Arabidopsis thaliana Root Development at a Cell Type-Specific Scale
Published on: May 14, 2020
Thermospermine drives dual-action ribosomes to shape plant xylem development
Hsin-Yen Larry Wu1, Polly Yingshan Hsu1
1Department of Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI 48824, USA.
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The formation of xylem vessels depends on a balance between transcription factors SACLs and LHW, whose translation is controlled by thermospermine. A recent study shows that a conserved rRNA methylation by OVERACHIEVER enables thermospermine binding, allowing ribosomes to oppositely regulate SACL and LHW translation to direct plant xylem cell fate.
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