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Implementation of a Reference Interferometer for Nanodetection
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Optical fiber-based nanoindenter featuring automated measurement.

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    This study introduces an improved fiber-optic nanomechanical probe (FONP) for precise measurements. The new system accurately characterizes materials like cells and polymers, demonstrating its potential for advanced nanomechanical analysis.

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    Area of Science:

    • Materials Science
    • Biophysics
    • Optical Engineering

    Background:

    • Nanoindentation is crucial for micro- and nanoscale mechanical testing.
    • Accurate measurements depend on high-resolution sensing and signal readout.
    • Existing methods may have limitations in stability and automation.

    Purpose of the Study:

    • To present an improved fiber-optic nanomechanical probe (FONP) and a dedicated automated nanoindentation system.
    • To demonstrate the system's accuracy, stability, and automation capabilities.
    • To investigate the mechanical properties of biological cells and polymer samples.

    Main Methods:

    • Fabrication of the FONP using femtosecond laser two-photon polymerization.
    • Development of a fiber-optic nanoindentation system with Fabry-Pérot interferometric optical readout.
    • Incorporation of an optical shielding layer for spectral stability without gold coating.
    • Automated array-based Young's modulus mapping and time-dependent mechanical evolution studies.

    Main Results:

    • The enhanced FONP achieved spectral stability with a cross-correlation coefficient of 1.
    • Investigated onion epidermal cells during dehydration, observing an increase in Young's modulus.
    • Automated Young's modulus mapping of PDMS samples showed <10% deviation from a commercial nanoindenter.

    Conclusions:

    • The proposed fiber-optic interferometric nanoindentation system offers accurate, stable, and automated nanomechanical characterization.
    • The system is suitable for investigating time-dependent mechanical properties of biological samples.
    • Demonstrated potential for compact and robust nanomechanical analysis in various scientific fields.