Related Experiment Video
Updated: May 5, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
Postpartum Management of Placenta Accreta with Transcervical Radiofrequency Ablation for Fertility Conservation
Nicole Santella1, David Toub2, Leslie Hansen Lindner3
1Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.
Abstract:
Background: Placenta accreta spectrum (PAS) refers to the abnormal placental implantation into the uterine wall, and its incidence is rising in parallel with increasing cesarean deliveries and myomectomies. PAS carries high maternal risks, including hemorrhage, shock, and death. Management involves either a hysterectomy or conservative approaches to preserve fertility that come with higher risks of maternal morbidity and mortality. Radiofrequency ablation (RFA) is a well-established modality for treating soft tissue tumors, but its use for PAS is not well studied. Case: We report a case of successful postpartum treatment of placenta accreta with transcervical radiofrequency ablation, which preserved uterine integrity and resolved significant bleeding without postoperative complications. Conclusions: Transcervical RFA may offer a safe and minimally invasive treatment for placenta accreta that conserves the uterus and may maintain reproductive capacity.

