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Reply to Hu et al

Kun Zhao1, Yash Pershad1, Alexander G Bick1

  • 1Division of Genetic Medicine and Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

Arthritis & Rheumatology (Hoboken, N.J.)
|May 4, 2026
PubMed
Summary

No abstract available in PubMed .

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Chi-square Analysis02:46

Chi-square Analysis

The chi-square test is a statistical hypothesis test. It is used to check whether there is a significant difference between an expected value and an observed value. In the context of genetics, it enables us to either accept or reject a hypothesis, based on how much the observed values deviate from the expected values.
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...