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Scanning Acoustic Microscopy as a Novel Quantitative Tool for Assessing Dermal Sclerosis in Systemic Sclerosis: A
Kyoko Kanno1, Satomi Igawa1, Masaru Honma1
1Department of Dermatology, Asahikawa Medical University, Asahikawa, Japan.
Case Reports in Dermatology
|May 4, 2026
Summary
Scanning acoustic microscopy (SAM) offers a quantitative method to assess skin fibrosis in Systemic Sclerosis (SSc). This technique detected early treatment response in SSc before changes in the modified Rodnan skin score (mRSS).
Area of Science:
- Rheumatology
- Dermatology
- Biomedical Engineering
Background:
- Systemic sclerosis (SSc) is a chronic autoimmune disease causing skin fibrosis and organ damage.
- Current monitoring relies on subjective scores like the modified Rodnan skin score (mRSS).
- Objective, quantitative methods are needed for better disease and treatment assessment in SSc.
